List of all WD firmware and software available for download.

If you’re under the impression that our Analog Discovery products are only Windows compatible, this post is for you. The Analog Discovery 2, Digital Discovery, and Analog Discovery Studio are ALL compatible with Windows, Mac, and Linux. That’s good because it makes our wonderful portable instruments even more accessible, but bad because it means that you have to admit that you were wrong in thinking that we weren’t looking out for you. In this post, we will be focusing on how to get your Analog Discovery Studio up and running on a Mac OS.

Getting Started With Digital Discovery (Mac) (Page has Moved) This guide has been replaced by Digital Discovery - Getting Started Guide, and is slated to be removed from the Digilent Wiki. Please update all bookmarks and saved links to the new location.
With Discovery Studio you can: Investigate and test hypotheses in silico prior to costly experimental implementation, thus reducing the time and expense involved in bringing products to market Drive scientific exploration from target identification to lead optimization with a wealth of trusted life science modeling and simulation tools.

Regardless of which type of OS you are using, the first thing you’re going to need to do is download WaveForms from the Resource Center, then you will need to do the following:

Open the .dmg file from the download location.
From the desktop, open the WaveForms Drive.
Move the WaveForms icon to the Applications folder.
The OS may block the launch of WaveForms when it is opened for the first time. If this is the case, go into the System Preferences’ Security and Privacy page and click Open Anyway.

And… if you’re working with a newer version of Mac OS, that’s it! However, if you are using OS-X 10.13 or earlier, you’ll have a few more steps to install some drivers. Luckily, we’re going to help you with Analog Discovery Studio even if you’re not caught up with the latest trends.

For OS-X 10.13 (or earlier):

Double click DigilentFtdiDriver.pkg to launch the FTDI Driver Installer.
Introduction > Continue
ReadMe > Continue
License > Continue > Agree
Destination Select > select users, then Continue
Install Type > Install
Voila!

Discovery Studio is a suite of software for simulating small molecule and macromolecule systems. It is developed and distributed by Dassault Systemes BIOVIA (formerly Accelrys).

The product suite has a strong academic collaboration programme, supporting scientific research and makes use of a number of software algorithms developed originally in the scientific community, including CHARMM,^[1]MODELLER,^[2]DELPHI,^[3] ZDOCK,^[4] DMol3^[5]^[6] and more.

Scope[edit]

Discovery Studio provides software applications covering the following areas:

Simulations
- Including Molecular Mechanics, Molecular Dynamics, Quantum Mechanics
- For molecular mechanics based simulations: Include implicit and explicit-based solvent models and membrane models
- Also includes the ability to perform hybrid QM/MM calculations
Ligand Design
- Including tools for enumerating molecular libraries and library optimization
Pharmacophore modeling
- Including creation, validation and virtual screening^[7]^[8]
Structure-based Design
- Including tools for fragment-based placement and refinement,^[9]receptor-ligand docking and pose refinement, de novo design
Macromolecule design and validation
Macromolecule engineering
- Specialist tools for protein-protein docking^[10]
- Specialist tools for Antibody design^[11] and optimization
- Specialist tools for membrane-bound proteins, including GPCRs
QSAR
- Covering methods such as multiple linear regression, partial least squares, recursive partitioning, Genetic Function approximation and 3D field-based QSAR
Predictive toxicity

External links[edit]

Supporting free software tools: Discovery Studio Visualizer and ActiveX Controls

Discovery Studio For Mac

References[edit]

^Brooks B. R., Brooks III C. L., Mackerell A. D., Nilsson L., Petrella R. J., Roux B., Won Y., Archontis G., Bartels C., Boresch S., Caflisch A., Caves L., Cui Q., Dinner A. R., Feig M., Fischer S., Gao J., Hodoscek M., Im W., Kuczera K., Lazaridis T., Ma J., Ovchinnikov V., Paci E., Pastor R. W., Post C. B., Pu J. Z., Schaefer M., Tidor B., Venable R. M., Woodcock H. L., Wu X., Yang W., York D. M. and Karplus M. CHARMM: The Biomolecular simulation Program, J. Comput. Chem.2009, 30, 1545-1615.
^Eswar N., Marti-Renom M.A., Webb B., Madhusudhan M.S., Eramian D., Shen M., Pieper U., Sali A. Comparative Protein Structure Modeling With MODELLER. Current Protocols in Bioinformatics, John Wiley & Sons, Inc., 2006, Supplement 15, 5.6.1-5.6.30.
^W.Rocchia, E.Alexov, and B.Honig. Extending the Applicability of the Nonlinear Poisson-Boltzmann Equation: Multiple Dielectric Constants and Multivalent Ions. J. Phys. Chem. B, 2001, 105, 6507-6514.
^Chen R., Weng Z. ZDOCK: An Initial-stage Protein-Docking Algorithm. Proteins2003, 52, 80-87.
^Matsuzawa N., Seto J., DixonD. A., J. Phys. Chem. A, 1997, 101, 9391.
^Delley Bi, J. Chem. Phys., 1990, 92, 508; ibid, 1991, 94, 7245; ibid, 2000, 7756.
^Sutter A., Jiabo L., Maynard A.J., Goupil A., Luu T., Katalin N., New Features that Improve the Pharmacophore Tools from Accelrys
^Luu T., Malcolm N., Nadassy K., Pharmacophore Modeling Methods in Focused Library Selection -Applications in the Context of a New Classification Scheme, Comb. Chem. & High Thr. Screening, 2011, 14(6), pp. 488-499(12)
^Haider M.K., Bertrand H.-O., Hubbard R.E., Predicting Fragment Binding Poses Using a Combined MCSS MM-GBSA Approach, J. Chem. Inf. Model., 2011, 51 (5), pp 1092–1105
^Corradia V., Mancinib M, Santuccib M.A., Carlomagnoc T., Sanfelicec D., Moria M., Vignarolia G., Falchia F., Manettia F., Radia M., Botta M., Computational techniques are valuable tools for the discovery of protein–protein interaction inhibitors: The 14-3-3σ case
^Almagro J.C., Beavers M.P., Hernandez-Guzman F., Maier J., Shaulsky J.,Butenhof K., Labute P., Thorsteinson N., Kelly K., Teplyakov A., Luo J., Sweet R., Gilliland G.L., Antibody modeling assessment, Proteins: Structure, Function, and Bioinformatics, 2011, 79(11), pages 3050–3066.

Discovery Studio Visualizer For Mac

Retrieved from 'https://en.wikipedia.org/w/index.php?title=Discovery_Studio&oldid=915151245'

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Discovery Studio For Mac

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Discovery Studio Visualizer For Mac